If you are working e.g. a lot with templates is helpful to the the API key of the fields on the page layouts instead of the field names.
This extension Salesforce API Fieldnames can help :-)
To work with profile (e.g. setting up sites users) can be annoying if you e.g. need to check a lot of check boxes. This extension allows this on a mouse click: Salesforce Admin Check All
Another great help to improve your productivity is the Salesforce inspector which allows to inspect data and metadata directly from the Salesforce UI.